Search on: COMPLEMENT C6 
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Descriptor English:   Complement C6 
Descriptor Spanish:   Complemento C6 
Descriptor Portuguese:   Complemento C6 
Tree Number:   D12.776.124.486.274.550
Definition English:   A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   2006 (1975) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   22138 
Unique Identifier:   D003183 

Occurrence in VHL:
 

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